| Autor: |
Algovik, Michael, Lagercrantz, Jacob, Westgren, Magnus, Nordenskjöld, Agneta |
| Zdroj: |
Human Reproduction; Oct1999, Vol. 14 Issue 10, p2451-2454, 4p |
| Abstrakt: |
Dystocia is a disorder characterized by prolonged or dysfunctional labour. Delivery that starts late or not at all, leads to an increased risk for Caesarean section, infant morbidity and mortality. Familial aggregations of dystocia suggest a polygenic background. We have studied three candidate genes for dystocia, i.e. the genes for testosterone 5-α reductase type 1, prostaglandin F2α receptor and endothelin 1 and performed mutational screening in 23 women with dystocia, of which 12 have affected relatives. No mutations were found, making it unlikely that any of these genes represent a major cause of dystocia in man. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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