Transmembrane signalling in human monocyte/mesangial cell co‐cultures: role of cytosolic Ca2+.

Autor: Menè, Paolo, Festuccia, Francescaromana, Polci, Rosaria, Pugliese, Francesco, Cinotti, Giulio A.
Zdroj: Nephrology Dialysis Transplantation; Jan2002, Vol. 17 Issue 1, p42-49, 8p
Abstrakt: Background. Adhesion of monocytes triggers apoptosis, cytotoxicity, cytokine release, and later proliferation of cultured human mesangial cells (HMC). In the search for transmembrane signals transducing the interaction of HMC adhesion molecules with leukocyte counterreceptors, we measured variations of cytosolic Ca2+ ([Ca2+]i) in HMC and monocytes of the U937 cell line during 6‐h co‐cultures. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index