Effect of acetate‐free biofiltration on the anaemia of haemodialysis patients: a prospective cross‐over study.

Autor: Basile, Carlo, Giordano, Rosa, Montanaro, Alessio, Maio, Pasquale De, Padova, Francesco De, Marangi, Anna Lisa, Semeraro, Angelo
Zdroj: Nephrology Dialysis Transplantation; Sep2001, Vol. 16 Issue 9, p1914-1919, 6p
Abstrakt: Background. The discussion about the pathogenesis of renal anaemia, whether it is primarily due to relative erythropoietin (Epo) deficiency or to uraemic inhibition of erythropoiesis, is still open. Although it has so far not been possible to identify or isolate a substance retained in uraemia with a suppressive action directed specifically against red‐cell production, dialysis therapy can improve the effect of both residual endogenous Epo and exogenous rHuEpo. To what extent the mode and/or the dose of dialysis influence Epo efficacy is as yet poorly understood. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index