| Autor: |
Nagano, Nobuo, Miyata, Sonoe, Obana, Sachiko, Ozai, Masako, Kobayashi, Nami, Fukushima, Naoshi, Burke, Steven K., Wada, Michihito |
| Zdroj: |
Nephrology Dialysis Transplantation; Sep2001, Vol. 16 Issue 9, p1870-1878, 9p |
| Abstrakt: |
Background. It has been demonstrated that dietary phosphate restriction suppresses parathyroid hormone (PTH) secretion and parathyroid cell proliferation in experimental animals with chronic renal insufficiency (CRI) independently of serum calcium and 1,25(OH)2D3 levels. This study was conducted to examine whether sevelamer hydrochloride (Renagel®; hereafter referred to as sevelamer), a non‐calcaemic phosphate binder could inhibit the parathyroid gland (PTG) hyperplasia in rats with progressive CRI. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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