Autor: |
Heller, Regine, Qing Chang, Ehrlich, Gunter, Hsieh, Sherry N., Schoenwaelder, Simone M., Kuhlencordt, Peter J., Preissner, Klaus T., Hirsch, Emilio, Wetzker, Reinhard |
Předmět: |
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Zdroj: |
Cardiovascular Research; Oct2008, Vol. 80 Issue 1, p96-105, 10p |
Abstrakt: |
Aims: Sphingosine-1-phosphate (S1P), a key regulator of vascular homeostasis and angiogenesis, promotes endothelial cell migration via stimulation of phosphoinositide 3-kinase (PI3K). The aim of this study was to identify the role of PI3Kβ and γ isoforms and their downstream effector pathways in mediating endothelial cell migration induced by S1P. [ABSTRACT FROM PUBLISHER] |
Databáze: |
Complementary Index |
Externí odkaz: |
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