Cryopreservation-induced human sperm DNA damage is predominantly mediated by oxidative stress rather than apoptosis.

Autor: Thomson, L. K., Fleming, S. D., Aitken, R. J., De Iuliis, G. N., Zieschang, J. -A., Clark, A. M.
Předmět:
Zdroj: Human Reproduction; Sep2009, Vol. 24 Issue 9, p2061-2070, 10p, 3 Diagrams, 1 Graph
Abstrakt: BACKGROUND: Whereas studies have revealed that the cryopreservation of human semen increases sperm DNA fragmentation, the mechanisms involved in this type of cryo-injury are largely unknown. Elucidation of these mechanisms may provide insight into preventing such injury. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index