| Autor: |
Young Min Bae, Chong-Woo Bae, Myung Ho Oh, Sang Han Lee, Kee Min Woo, Keum Bun Jung |
| Předmět: |
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| Zdroj: |
Journal of Perinatal Medicine; 2009, Vol. 37 Issue 5, p561-564, 4p, 1 Black and White Photograph, 2 Graphs |
| Abstrakt: |
Objectives: To examine whether exogenous pulmonary surfactants (exPS) substitute for or merely supplement endogenous pulmonary surfactants (enPS) by looking at sequential changes in the surfactant proteins (SP) SP-A and SP-D in alveolar pools. Methods: Fourteen preterm infants with RDS treated with an artificial surfactant were compared to five normal-term infants without RDS who were treated with artificial ventilation at birth. Results: Immediately after birth, SP-A and SP-D were essentially absent in the alveolar pools of the RDS group, but were present at normal levels in the controls. Treatment with exPS apparently stimulated enPS production. Conclusions: In infants who responded well to exPS therapy, the SP concentration reached essentially normal levels within 48–72 h after birth. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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