| Autor: |
Patenaude, A., Rodriguez-Leyva, D., Edel, A. L., Dibrov, E., Dupasquier, C. M. C., Austria, J. A., Richard, M. N., Chahine, M. N., Malcolmson, L. J., Pierce, G. N. |
| Předmět: |
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| Zdroj: |
European Journal of Clinical Nutrition; Sep2009, Vol. 63 Issue 9, p1123-1129, 7p, 6 Charts, 1 Graph |
| Abstrakt: |
Background:Dietary flaxseed may have beneficial cardiovascular effects. An aged population has a higher incidence of cardiovascular disease, but they may react differently to flaxseed in the diet.Objective:To investigate the response, over a period of 4 weeks, of subjects aged 18–29 or 45–69 years to a diet containing the same amount of α-linolenic acid (ALA) (6 g) introduced in the form of ground flaxseed (30 g) or flaxseed oil.Results:All subjects who received flaxseed oil showed a significant increase in plasma ALA and eicosapentaenoic acid (EPA) concentrations over the course of this study. Subjects who received ground flaxseed in the 18–29-year-old group showed a statistically significant increase in their plasma ALA levels, and although there was a trend in the same direction for the 45–69-year-old subjects, this did not achieve statistical significance. The diets induced no major changes in platelet aggregation, plasma total cholesterol, low-density lipoprotein or high-density lipoprotein cholesterol levels in any of the groups. Younger subjects showed a decrease in triglyceride (TG) values compared with older subjects. There were no significant side effects that caused compliancy issues.Conclusion:Subject age does not seem to be a major determining factor in influencing ALA absorption from a flaxseed-supplemented diet nor in the metabolism of ALA to EPA in the groups fed flaxseed oil. Concerns about side effects in older subjects administered a higher fiber load in a flaxseed-supplemented diet are not justified. However, younger but not older subjects showed a beneficial decrease in circulating TGs due to flaxseed supplementation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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