| Autor: |
Geurs, Nicolaas C., Korostoff, Jonathan M., Vassilopoulos, Philip J., Tae-Heon Kang, Jeffcoat, Marjorie, Kellar, Robert, Reddy, Michael S. |
| Předmět: |
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| Zdroj: |
Journal of Periodontology; Jul2008, Vol. 79 Issue 7, p1133-1140, 8p, 3 Diagrams, 2 Charts, 1 Graph |
| Abstrakt: |
Background: Guided bone regeneration (GBR) is a widely used procedure for augmenting alveolar ridge width prior to placement of endosseous implants. Various graft materials and barrier membranes (non-resorbable and bioabsorbable) have been used in GBR. The aim of this study was to assess the performance of a new bioabsorbable, synthetic polyglycolic acid/trimethylene carbonate (PGA/TMC) barrier membrane with an increased absorption time in conjunction with a combination of assayed demineralized bone matrix and cortical cancellous chips uniformly dispersed in a thermoplastic biologic carrier. Methods: At 72 potential implant sites in 38 subjects, ridge width at the crest and 4 mm apical to the crest was measured be fore and 6 months after a GBR procedure using the long term (LT) PGA/TMC membrane and an allograft in a thermoplastic carrier. Before placement of endosseous implants, 48 biopsy specimens were obtained from the augmentation sites and analyzed histomorphometrically. Results: The GBR procedure increased the mean ridge width at the crest from 2.4 to 5.2 mm. This 216% change from baseline was significant (P<0.001). The mean width 4 mm apical to the crest in creased from 4.4 to 7.5 mm, a significant (P<0.001 ) 174% change. The histomorphometric analysis showed that the biopsy specimens consisted, on average, of 57% bone (36% graft material and 21% new bone) and 43% soft tissue and space. Conclusion: Our findings suggest that the LT PGA/TMC barrier membrane, used in conjunction with an allograft, provides lateral alveolar ridge augmentation comparable to that achieved with other materials without the necessity for bone-graft harvesting or a second procedure to remove the barrier membrane. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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