NH[sub 2]-terminal modification of a channel-forming peptide increases capacity for epithelial...

Autor: Broughman, James R., Mitchell, Kathy E., Sedlacek, Roger L., Iwamoto, Takeo, Tomich, John M., Schultz, Bruce D.
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Zdroj: American Journal of Physiology: Cell Physiology; Mar2001, Vol. 280 Issue 3, pC451, 8p, 1 Chart, 16 Graphs
Abstrakt: Focuses on the NH[sub 2]-terminal modification a synthetic, channel-forming peptide, derived from the alpha-subunit of the glycine receptor, through the addition of four lysine residues to the NH[sub 2] terminus. Effect on transepithelial ion transport; Concentration dependence of the modified peptide-mediated anion secretion.
Databáze: Complementary Index