| Autor: |
Noll, Robert B., Stith, Laura, Gartstein, Maria A., Ris, M. Douglas, Grueneich, Royal, Vannatta, Kathryn, Kalinyak, Karen, Noll, R B, Stith, L, Gartstein, M A, Ris, M D, Grueneich, R, Vannatta, K, Kalinyak, K |
| Předmět: |
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| Zdroj: |
Journal of Pediatric Psychology; Mar2001, Vol. 26 Issue 2, p69-78, 10p, 3 Charts |
| Abstrakt: |
Objective: To compare the neuropsychological functioning of children with sickle cell disease (SCD) with no evidence of overt clinical stroke to that of classmates without a chronic illness matched on gender, race, and age. We examined both overall level of performance and patterns of performance utilizing empirically derived construct scores of key domains of neurocognitive functioning.Methods: An abbreviated neuropsychological battery of tests was given to 31 children with SCD and 31 case controls. Empirically derived construct scores were developed for primary analyses.Results: Children with SCD had significantly lower scores on three level-of-performance construct scores: total, verbal, and attention/memory. Mean scores for children with SCD were lower than those for case controls on every level-of-performance construct score and every standardized test score. However, pattern-of-performance construct scores were not significantly different.Conclusions: Children with SCD without overt stroke demonstrate significant deficits in neurocognitive functioning compared to classroom case controls. These findings highlight the impact of SCD on general neurocognitive functioning and suggest that routine screening of cognitive functioning should be a requisite element of comprehensive care for children with SCD. Within the context of documented physical limitations, we conclude that children with SCD are at very high risk for impaired psychosocial outcomes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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