Efficient and convenient preparation of 3-aryl-2,2-dimethylpropanoates via Negishi coupling.

Autor: Kwak, Young-Shin, Kanter, Aaron D., Wang, Bing, Liu, Yugang
Předmět:
Zdroj: Chemical Communications; Apr2009, Vol. 2009 Issue 16, p2145-2147, 3p
Abstrakt: An efficient and convenient Negishi coupling protocol was developed for the preparation of 3-aryl-2,2-dimethylpropanoates providing easy access to key pharmaceutical intermediates that often require multi-step synthesis using conventional enolate chemistry. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index