Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of...
Autor: | Salomon, Arthur R., Voehringer, David W. |
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Zdroj: | Proceedings of the National Academy of Sciences of the United States of America; 12/19/2000, Vol. 97 Issue 26, p14766, 6p, 4 Diagrams, 1 Chart, 8 Graphs |
Abstrakt: | Studies the mechanistic basis for the selectivity of the polyketide inhibitor of a selective cancer cell line cytotoxic agent. Proposed strategy to desensitize tumor cells that do not exhibit the Warburg effect; Role of macrolides inhibitors in the selective killing of tumor cells. |
Databáze: | Complementary Index |
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