Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of...

Autor: Salomon, Arthur R., Voehringer, David W.
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 12/19/2000, Vol. 97 Issue 26, p14766, 6p, 4 Diagrams, 1 Chart, 8 Graphs
Abstrakt: Studies the mechanistic basis for the selectivity of the polyketide inhibitor of a selective cancer cell line cytotoxic agent. Proposed strategy to desensitize tumor cells that do not exhibit the Warburg effect; Role of macrolides inhibitors in the selective killing of tumor cells.
Databáze: Complementary Index