Vibrational spectroscopy: a clinical tool for cancer diagnosticsThis paper is part of an Analystthemed issue on Optical Diagnosis. The issue includes work which was presented at SPEC 2008 Shedding Light on Disease: Optical Diagnosis for the New Millennium, which was held in São José dos Campos, São Paulo, Brazil, October 25–29, 2008.

Autor: Catherine Kendall, Martin Isabelle, Florian Bazant-Hegemark, Joanne Hutchings, Linda Orr, Jaspreet Babrah, Rebecca Baker, Nicholas Stone
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Zdroj: Analyst; Jun2009, Vol. 134 Issue 6, p1029-1045, 17p
Abstrakt: Vibrational spectroscopy techniques have demonstrated potential to provide non-destructive, rapid, clinically relevant diagnostic information. Early detection is the most important factor in the prevention of cancer. Raman and infrared spectroscopy enable the biochemical signatures from biological tissues to be extracted and analysed. In conjunction with advanced chemometrics such measurements can contribute to the diagnostic assessment of biological material. This paper also illustrates the complementary advantage of using Raman and FTIR spectroscopy technologies together. Clinical requirements are increasingly met by technological developments which show promise to become a clinical reality. This review summarises recent advances in vibrational spectroscopy and their impact on the diagnosis of cancer. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index