l-Carnosine: multifunctional dipeptide buffer for sustained-duration topical ophthalmic formulations.

Autor: Swita Singh, Samantha Carreiro, Jessie Chu, Ganesh Prasanna, Michael Niesman, Walter Collette, Husam Younis, Soisurin Sartnurak, Hovhannes Gukasyan
Předmět:
Zdroj: Journal of Pharmacy & Pharmacology; Jun2009, Vol. 61 Issue 6, p733-742, 10p
Abstrakt: The article presents a study which explored L-carnosine's use as a buffer in gellan gum. The study evaluated the buffer capacity and determined the accelerated chemical stability through high-performance liquid chromatography (HPLC). Results revealed the optimal pharmaceutical characteristics shown by L-Carnosine as a buffer in topical ocular formulations.
Databáze: Complementary Index