PEDIATRIC THYROID CARCINOMA: 22 Years of Experience at the Northern Israel Oncology Center (1973-1995).

Autor: Arush, Myriam Weyl Ben, Stein, Moshe E., Nahum, Monica Perez, Zidan, Jamal, Kuten, Abraham
Předmět:
Zdroj: Pediatric Hematology & Oncology; Jan2000, Vol. 17 Issue 1, p85-92, 8p
Abstrakt: Over the past 22 years, 16 children with thyroid carcinoma were referred to the Northern Israel Oncology Center. All patients had undergone surgical procedures, either total or subtotal thyroidectomy, and 7 patients had undergone cervical lymph node dissections. Postoperatively, 5 patients underwent thyroid ablation with radioactive [sup 131]I as first treatment. Two patients received postoperative external radiation therapy to a field encompassing the cervical region, superior mediastinum, and both supraclavicular grooves. After a median follow-up of 60 months (range, 5-169 months), all patients are alive with no evidence of recurrent disease. Two patients who had recurrences, one in the submaxillary lymph nodes and one in the lungs, were salvaged successfully with retreatment with [sup 131]I therapy. No severe acute or long-term side effects were exhibited. The long-term results of treatment of pediatric thyroid carcinoma are excellent, but there remains disagreement over the extent of surgical and postsurgical treatment required. [ABSTRACT FROM AUTHOR]
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