| Autor: |
El-Nezhawy, A. O. H., El-Naem, S. I., Galal, S. A., El-Diwani, H. I., Abdel Salam, O. M. E., Baiomy, A. R. |
| Předmět: |
|
| Zdroj: |
Pharmaceutical Chemistry Journal; Jan2009, Vol. 43 Issue 1, p25-29, 5p, 3 Diagrams, 3 Charts |
| Abstrakt: |
Series of 1,4-disubstituted piperazine and of N,N-disubstituted ethylenediamine having the 2,3-diphenyl- 1H-indole-5-carbonyl group as one of the two substituents were prepared. Compounds 3, 4, 11, 15 – 17, and 20 – 22 were tested for analgesic activity. After ip administration all compounds induced significant visceral antinociceptive activities where acetic acid-induced writhing was significantly reduced by all compounds. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
