Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells.

Autor: Yoshida, Tatsushi, Horinaka, Mano, Takara, Mami, Tsuchihashi, Mayuko, Mukai, Nobuhiro, Wakada, Miki, Sakai, Toshiyuki
Zdroj: Environmental Health & Preventive Medicine; 2008, Vol. 13 Issue 5, p281-287, 7p
Abstrakt: The article reports on the study on the combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) overcomes apoptosis in colon cancer HT29 cells. It shows that a single treatment with isoliquiritigenin scarcely induced apoptosis in HT29 cells. Also, combined treatment with suboptimal concentrations of isoliquiritigenin and TRAIL markedly induced apoptosis.
Databáze: Complementary Index
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