| Autor: |
Yunbo Liu, Maruvada, Subha, King, Randy L., Herman, Bruce A., Wear, Keith A. |
| Předmět: |
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| Zdroj: |
AIP Conference Proceedings; 4/14/2009, Vol. 1113 Issue 1, p291-295, 5p, 1 Chart, 3 Graphs |
| Abstrakt: |
A blood mimicking fluid (BMF) has been developed and characterized in a temperature dependent manner for high intensity focused ultrasound (HIFU) ablation devices. The BMF is based on a degassed and de-ionized water solution dispersed with low density polyethylene micro-spheres, nylon particles, gellan gum and glycerol. A broad range of physical parameters, including frequency dependent ultrasound attenuation, speed of sound, viscosity, thermal conductivity and diffusivity were characterized as a function of temperature (20° C to 70° C). The nonlinear parameter B/A and backscatter coefficient were also measured at room temperature. The attenuation coefficient is linearly proportional to the frequency (2 MHz–8 MHz) with a slope of about 0.2 dB cm-1 MHz-1 in the 20° C to 70° C range as has been reported for human blood. All the other temperature dependent physical parameters are also close to the reported values in human blood. These properties make the BMF a useful HIFU research tool for developing standardized exposimetry techniques, validating numerical models, and determining the safety and efficacy of HIFU ablation devices. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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