Synthesis and coronary vasodilating activity of 1-aminopyrazolo[3,4- b]pyridines with fused tetrahydropyran (-thiopyran) and piperidine rings.

Autor: Dabaeva, V., Pilosyan, S., Noravyan, A., Bagdasaryan, M., Grigoryan, G., Aleksanyan, R.
Předmět:
Zdroj: Pharmaceutical Chemistry Journal; Dec2008, Vol. 42 Issue 12, p668-669, 2p, 2 Charts
Abstrakt: Methods for the synthesis of 6,6-substituted 1-aminopyrazolo[3,4- b]pyridines with fused tetrahydropyran (-thiopyran) and pyridine rings have been developed on the basis of condensed 2-chloropyridine derivatives. The coronary vasodilating activity of the synthesized compounds has been studied. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index