Osteoblast Responses to BMP-2--Treated Titanium In Vitro.

Autor: Ong, Joo L., Cardenas, Lee, Cavin, Renée, Carnes Jr., David L.
Předmět:
Zdroj: International Journal of Oral & Maxillofacial Implants; 1997, Vol. 12 Issue 5, Special section p1-7, 7p, 3 Graphs
Abstrakt: In this study, the phenotypic expression of osteoblast progenitor cells, 2T9, on characterized titanium surfaces was examined in the presence of a bone morphogenetic protein-2 (BMP-2). X-ray photoelectron spectroscopy spectra indicated the presence of titanium dioxide on titanium surfaces, along with surface contaminants such as carbon and nitrogen. In the in vitro study, the activity of BMP-2-treated osteoblast cells on titanium surfaces was marked by significantly higher alkaline phosphatase-specific activity and 1,25 (OH2) vitamin D3-stimulated osteocalcin production when compared to the untreated cells on titanium surfaces. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index