Decrease of Renal Function due to Warm Ischemia after Laparoscopic Partial Nephrectomy: Evaluation Using Tc-DMSA Renal Scintigraphy.

Autor: Tachikake, Toshihiro, Shigeta, Masanobu, Mita, Koji, Marukawa, Kazushi, Usui, Tsuguru, Ito, Katsuhide
Předmět:
Zdroj: Urologia Internationalis; Feb2009, Vol. 82 Issue 2, p162-165, 4p, 1 Black and White Photograph, 1 Graph
Abstrakt: Introduction: The purpose of this study is, using technetium-99m-dimercaptosuccinic acid (99mTc-DMSA), to evaluate the decrease of renal function caused by warm ischemia. Patients and Methods: The 99mTc-DMSA scan was performed before and 1, 3 and 6 months after the operation for 19 consecutive patients. The patients were divided into three groups by warm ischemic time (group A: ≤40 min, B: >40 min ∩ ≤60 min, C: >60 min). Renal function of the unresected part was defined as the uptake to unresected part relative to the uptake to the contralateral kidney. The reduction of renal function was expressed as a ratio of the function after the surgery divided by function before the surgery and was compared between the three groups. Results: The reduction in group C after 1 and 3 months tended to be greater than that in group A or B, although not reaching statistical significance (one-way ANOVA test, 1 month: p = 0.15 and 3 months: p = 0.13). There was a significant difference in reduction of renal function between the three groups after 6 months (one-way ANOVA test, p = 0.02). The Scheffé test showed a statistical significance between groups A and C (p < 0.05). Conclusion: Renal function calculated by 99mTc-DMSA shows that prolonged ischemic time causes significant damage to the kidney. Copyright © 2009 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index