Autor: |
Sunho Oh, Tobin, Eric, Yunzhi Yang, David L. Carnes, Joo L. Ong |
Předmět: |
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Zdroj: |
International Journal of Oral & Maxillofacial Implants; Sep/Oct2005, Vol. 20 Issue 5, p726-731, 6p, 2 Color Photographs, 1 Chart, 1 Graph |
Abstrakt: |
Purpose: The influence of calcium phosphate (CaP) and hydroxyapatite (HA) crystallinity on boneimplant osseointegration is not well established. In this study, the effect of HA crystallinity and coating method on bone-implant osseointegration was investigated using a rat tibia model. Materials and Methods: HA coatings 1 to 5 μm thick were produced using a supersonic particle acceleration (SPA) technology. The HA crystallinities used for this study were weight ratios of 30%, 50%, 70%, and 90%. A total of 128 HA-coated implants were placed into the tibiae of 64 male Sprague-Dawley rats. Boneimplant interfaces were evaluated using histology and push-out strength testing at 3 and 9 weeks after implantation. Results: The 70% crystalline coatings exhibited significantly greater interfacial strength (5 implants/time point/treatment) than the 30%, 50%, and 90% crystalline coatings at 3 and 9 weeks following implantation. The implants with coatings of 70% crystallinity also had the greatest bone contact length. In addition, the HA coatings produced with SPA demonstrated greater interfacial strength and bone contact length than plasma-sprayed HA coatings (except for the HA coating with 30% crystallinity). Discussion: HA coatings of different crystallinities exhibited different dissolution and re-precipitation properties which may enhance early bone formation and bone bonding. Conclusions: This study suggested that coating crystallinity and coating methods can influence the bone-implant interface. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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