| Autor: |
GENCO, ROBERT J., EMMINGS, FRED G., EVANS, R. TODD, APICELLA, MICHAEL |
| Předmět: |
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| Zdroj: |
Journal of Dental Research; Apr1976 Supplement 3, Vol. 55, pC115-C120, 6p, 2 Charts, 1 Graph |
| Abstrakt: |
The article presents research into the purification, characterization, and immunogenicity of cell-associated glucan from Streptococcus mutans (S mutans) associated with dental caries in rats. Particular attention is paid to the antigens glucosyltransferases and gulcans that may reduce the establishment of S mutans in the oral cavity. Researchers look to purify insoluble glucans from S mutans strain 6715 cells, develop an assay to measure serum and salivary antibodies, and study the salivary immunogloblulin A (IgA) response in monkeys. Results revealed that immunization with whole cell vaccines of S mutans appeared to induce antibodies that inhibit S mutans implantation on tooth surfaces and associated dental caries. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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