Intrafibrillar Mineral May be Absent in Dentinogenesis Imperfecta Type II (DI-II).

Autor: Kinney, J. H., Pople, J. A., Driessen, C. H., Breunig, T. M., Marshall, G. W., Marshall, S. J.
Předmět:
Zdroj: Journal of Dental Research; Jun2001, Vol. 80 Issue 6, p1555-1559, 5p, 2 Color Photographs, 2 Graphs
Abstrakt: High-resolution synchrotron radiation computed tomography (SRCT) and small-angle x-ray scattering (SAXS) were performed on normal and dentinogenesis imperfecta type II (DI-II) teeth. The SRCT showed that the mineral concentration was 33% lower on average in the DI-II dentin with respect to normal dentin. The SAXS spectra from normal dentin exhibited low-angle diffraction peaks at harmonics of 67.6 nm, consistent with nucleation and growth of the apatite phase within gaps in the collagen fibrils (intrafibrillar mineralization). In contrast, the low-angle peaks were almost non-existent in the DI-II dentin. Crystallite thickness was independent of location in both DI-II and normal dentin, although the crystallites were significantly thicker in DI-II dentin (6.8 nm [SD =0.5] vs. 5.1 nm [SD =0.6]). The shape factor of the crystallites, as determined by SAXS, showed a continuous progression in normal dentin from roughly one-dimensional (needle-like) near the pulp to two-dimensional (plate-like) near the dentin-enamel junction. The crystallites in DI-II dentin, on the other hand, remained needle-like throughout. The above observations are consistent with an absence of intrafibrillar mineral in DI-II dentin. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index