| Autor: |
Wun-Rong Hong, Mei Ge, Zhi-Hong Zeng, Li Zhu, Min-Yu Luo, Lei Shao, Dai-Jie Chen |
| Předmět: |
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| Zdroj: |
Biotechnology Letters; Mar2009, Vol. 31 Issue 3, p449-455, 7p, 3 Diagrams, 1 Chart |
| Abstrakt: |
Micromonospora inyoensis produces sisomicin (Sm), an aminoglycoside antibiotic. The gene cluster of sisomicin biosynthesis spanning ca. 47 kb consists of 37 ORFs encoding various proteins for sisomicin biosynthesis, regulation, resistance and transport. The comparative genetic studies on the biosynthetic genes of sisomicin and gentamicin (Gm) reveal a similar biosynthetic route and provide a framework for the future biosynthetic studies. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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