147: Correlation of Serum Testosterone Level with Insulin Resistance and Metabolic Syndrome.

Autor: Kim, Sae-Chul, Lee, So Yun
Předmět:
Zdroj: Indian Journal of Urology; Supplement2, Vol. 24, pS103-S103, 1/5p
Abstrakt: Introduction: Recently, testosterone deficiency has captured attention to be a possible risk factor of the metabolic syndrome. This study was conducted to investigate a correlation of serum testosterone level with insulin resistance (IR) and metabolic syndrome (MS). Methods: On a total of 215 patients (mean age; 61.04±0.54 years) with erectile dysfunction or/and benign prostatic hyperplasia, metabolic risk factors - fasting serum glucose, triglyceride, and high density lipoprotein (HDL) cholesterol were measured with blood pressure and waist circumference. Serum total testosterone and insulin were measured at the same time, and free testosterone, bioavailable testosterone, and IR were calculated. Results: The prevalence of MS and the number of associated MS risk factors were significantly higher in insulin resistance group (IRG) than in insulin sensitive group (ISG). The serum testosterone level significantly decreased with more risk factors. IRG showed significantly lower level of serum testosterone than ISG. Conclusions: The negative correlation of decrease in serum testosterone level with IR and MS suggests that late onset hypogonadism might be a risk factor of MS. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index