Tumor Necrosis Factor α Drives Cadherin 11 Expression in Rheumatoid Inflammation.

Autor:	Vandooren, Bernard, Cantaert, Tineke, ter Borg, Mariëtte, Noordenbos, Troy, Kuhlman, Rodger, Gerlag, Danielle, Bongartz, Tim, Reedquist, Kris, Tak, Paul P., Baeten, Dominique
Předmět:	INFLAMMATORY mediators CADHERINS TUMOR necrosis factors RHEUMATOID arthritis POLYMERASE chain reaction WESTERN immunoblotting CELLULAR control mechanisms
Zdroj:	Arthritis & Rheumatism; Oct2008, Vol. 58 Issue 10, p3051-3062, 12p, 3 Color Photographs, 2 Charts, 1 Graph
Abstrakt:	The article presents a study on the Cadherin 11 expression on fibrolast-like synoviocytes by tumor necrosis factor mediation in rheumatoid inflammation. Synovial samples from arthritis patients and lung biopsy samples from interstitial pneumonitis (IP) patients were analyzed by immunostaining. The cadherin 11 expression regulation in fibrolasts was evaluated using quantitative reverse transcription polymerase chain reaction analysis and Western blotting.
Databáze:	Complementary Index
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