Roles of BRCA1 and its interacting proteins.

Autor: Chu-Xia Deng, Brodie, Steven G.
Předmět:
Zdroj: BioEssays; Aug2000, Vol. 22 Issue 8, p728, 10p, 3 Diagrams, 1 Chart
Abstrakt: Focuses on a study that examined the significance of the interactions between the breast cancer associated gene 1 (BRCA1) and other proteins. Role of the germline mutations of BRCA1 in breast and ovarian cancers; Roles of the BRCA1 tumor suppressor gene in several cellular pathways; Involvement of BRCA1 in DNA-damage repair and centrosome duplication.
Databáze: Complementary Index