| Abstrakt: |
Deer antler is a rare example of a fast-growing organ in the higher animal kingdom. Regenerating antlers provide a unique opportunity to study rapid growth and development at the cellular and molecular levels. The tip, upper section, mid section, and base of the antler have different biological properties. In the present study, gene expression profiling was carried out in these four parts using DNA chip microarray technology. Three sets of comparisons were done, tip vs. base, upper section vs. base, and mid section vs. base. Among the genes analyzed, there were 84 up-regulated in the comparison tip vs. base, 39 in the upper section vs. base, and eight in the mid-section vs base. In addition, 132, 72, and 31 down-regulated genes were identified in the same comparisons, respectively. Characterization of these genes may lead to the disclosure of the secret resides in the functions between the base of the developing antlers and the other three upper parts of that. [ABSTRACT FROM AUTHOR] |
