| Abstrakt: |
Abstract Menstrual and reproductive factors may increase breast cancer risk through a pathway that includes increased mammographic density. We assessed whether known or suspected menstrual and reproductive breast cancer risk factors were cross-sectionally associated with mammographic density, by measuring area of radiographic density and total breast area on mammograms from 801 participants in the Study of Women’s Health Across the Nation (SWAN), a multi-ethnic cohort of pre- and early perimenopausal women. From multivariable linear regression, the following menstrual or reproductive factors were independently associated with percent mammographic density (area of dense breast/breast area): older age at menarche (β = 10.3, P 13 vs. β = −3.36, P = 0.02), younger age at first full-term birth (β = −8.12, P β = −6.80, P β = 3.78, P β = −12.2, P [ABSTRACT FROM AUTHOR] |
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