| Autor: |
Simonenko, A. V., Rybina, O. Yu., Pasyukova, E. G. |
| Předmět: |
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| Zdroj: |
Russian Journal of Genetics; Sep2008, Vol. 44 Issue 9, p1020-1024, 5p, 1 Diagram, 1 Chart |
| Abstrakt: |
Comparative polymorphism of the first exon and first intron of the shuttle craft ( stc) and Lim3 genes and their putative regulatory 5′-flanking sequences was analyzed using 20 sequenced natural alleles. A comparison of the stc and Lim3 genes showed that the extent of polymorphism was similar in their introns and corresponded to the variation level characteristic of Drosophila melanogaster, while the putative regulatory region and first intron of the stc gene proved to be more variable than the corresponding regions of the Lim3 gene. Since the genes under study occurred on the same chromosomes isolated from one population and were close together in a region having a high recombination rate, the difference in the extent of polymorphism between the regulatory and coding regions was explained by individual characteristics of each gene. The results made it possible to assume that the extent of polymorphism of the coding gene regions is maintained by balancing selection. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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