| Autor: |
Artandi, Steven E., Chang, Sandy, Shwu-Luan Lee, Alson, Scott, Gottlieb, Geoffrey J., Chin, Lynda, DePinho, Ronald A. |
| Předmět: |
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| Zdroj: |
Nature; 8/10/2000, Vol. 406 Issue 6796, p641, 5p, 11 Color Photographs, 1 Chart, 3 Graphs |
| Abstrakt: |
Presents a study which provides evidence that telomere attrition in ageing telomerase-deficient p53 mutant mice promotes the development of epithelial cancers by a process of fusion-bridge breakage that leads to the formation of complex non-reciprocal translocations. Methods; Results; Conclusion. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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