| Autor: |
Benjamin Kipp, Harmony Tyner, Michael Campion, Jesse Voss, R. Karnes, Thomas Sebo, Kevin Halling, Jun Zhang |
| Předmět: |
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| Zdroj: |
American Journal of Clinical Pathology; Oct2008, Vol. 130 Issue 4, p552-559, 8p |
| Abstrakt: |
Fluorescence in situ hybridization (FISH) with the UroVysion probe set (Abbott Molecular, Des Plaines, IL) was used to assess 31 bladder cancers for chromosomal abnormalities, including 4 adenocarcinomas, 5 urachal adenocarcinomas, 6 small cell carcinomas, 7 squamous cell carcinomas, and 9 typical urothelial carcinomas. FISH was also used to assess the benign urothelium in 4 cases. There was a significant increase (P 75%) demonstrating homozygous 9p21 deletion. The data from this study suggest that chromosomal abnormalities detectable by FISH in urothelial carcinoma are also common in rarer histologic variants of bladder cancer. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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