| Autor: |
Miële, A., Blanchin, N., Raynaud, P., Quesne, B., Giraud, J. M., Fottorino, R., Bérard, P., Ansoborlo, E., Franck, D., Blanchardon, E., Challeton-de Vathaire, C., Lebaron-jacobs, L., Poncy, J. L., Piechowski, J., Fritsch, P. |
| Předmět: |
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| Zdroj: |
Radiation Protection Dosimetry; 2007 Special Issue, Vol. 127 Issue 1-4, p350-355, 6p, 2 Charts, 1 Graph |
| Abstrakt: |
A didactic software, MEthodes DOsímètriques de REférence (MEDOR), is being developed to provide help in the interpretation of biological data. Its main purpose is to evaluate the pertinence of the application of different models. This paper describes its first version that is focused on inhalation exposure to actinide aerosols. With this tool, sensitivity analysis on different parameters of the ICRP models can be easily done for aerosol deposition, in terms of activity and particle number, actinide biokinetics and doses. The user can analyse different inhalation cases showing either that dose per unit intake cannot be applied if the aerosol contains a low number of particles or that an inhibition of the late pulmonary clearance by particle transport can occur which contributes to a 3-4 fold increase in effective dose as compared with application of default parameters. This underlines the need to estimate systematically the number of deposited particles, as well as to do chest monitoring as long as possible. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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