Autor: |
Willerson, James T., Wellens, Hein J. J., Cohn, Jay N., Holmes, David R., Cheitlin, Melvin D., Hsue, Priscilla, Sande, Merle A. |
Zdroj: |
Cardiovascular Medicine; 2007, p2371-2384, 14p |
Abstrakt: |
From the very beginning of the epidemic of human immunodeficiency virus (HIV) infection, which surfaced in the late 1970s, involvement of the heart was described in autopsies of patients who had died of the acquired immune deficiency syndrome (AIDS). The early reports described Kaposi's sarcoma involving the myocardium and pericardium,1,2 often as incidental findings at autopsy. Large series of patients with AIDS described nonbacterial thrombotic endocarditis, a possibly nonspecific finding resulting from the severe cachexia and wasting frequently seen with this disease.3,4 Later, larger autopsy series showed frequent evidence of focal pockets of inflammatory cells in the myocardium, at times with incidental findings of fungal or parasitic involvement of the myocardium, but clinical manifestations of this myocardial involvement were unusual. Rarely, severe myocarditis due to toxoplasmosis was seen as a cause of death. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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