Autor: |
Sharma, Kamal, Leonard, Ann E., Lettieri, Karen, Pfaff, Samuel L. |
Předmět: |
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Zdroj: |
Nature; 8/3/2000, Vol. 406 Issue 6795, p515, 5p, 30 Color Photographs, 2 Diagrams, 1 Graph |
Abstrakt: |
Investigates the nonspecific versus genetically controlled regulation of motor connectivity. Method of forcing all motor neurons to express ectopically a LIM gene combination appropriate for the subgroup that innervates axial muscles; Evidence that the genetic alteration is sufficient to convert the cell body settling pattern, gene-expression profile and axonal projections of all motor neurons to that of the axial subclass. |
Databáze: |
Complementary Index |
Externí odkaz: |
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