| Autor: |
L. Ermolaeva, T. Dubskaya, T. Fomina, T. Vetoshkina, V. Gol’dberg |
| Předmět: |
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| Zdroj: |
Bulletin of Experimental Biology & Medicine; Feb2008, Vol. 145 Issue 2, p263-265, 3p |
| Abstrakt: |
Abstract Single intravenous injection of paclitaxel to rats in a maximum tolerated dose of 4.6 mg/kg was accompanied by permanent structural and functional changes in the liver. The observed changes were typical of nonspecific reactive hepatitis: infiltration with lymphocytes and macrophages, pyknosis, and focal fatty degeneration of hepatocytes. Liver enzyme activity increased in blood plasma. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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