Inhibition of Azoxymethane-Induced Colon Cancer by Orange Juice.

Autor:	Miyagi, Y., Om, A. S., Chee, K. M., Bennink, M. R.
Předmět:	ORANGE juice COLON cancer PHYSIOLOGY
Zdroj:	Nutrition & Cancer; 2000, Vol. 36 Issue 2, p224-229, 6p, 4 Charts
Abstrakt:	Abstract: Previous research has shown that hesperidin, a flavanone glycoside in orange juice, inhibits colon carcinogenesis and that feeding double-strength orange juice delays the onset of chemically induced mammary cancer in rats. This study determined whether feeding single-strength, pasteurized orange juice would inhibit azoxymethane (AOM)-induced colon cancer in male Fischer 344 rats. Colon cancer was initiated by injecting AOM (15 mg/kg body wt) at 22 and 29 days of age. One week after the second AOM injection, orange juice replaced drinking water for the experimental group (n + 30). The rats were killed 28 weeks later, and tumors were removed for histological analysis. Feeding orange juice reduced tumor incidence by 22% (p <> . [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.