Skin prick test of Kudoa sp. antigens in patients with gastrointestinal and/or allergic symptoms related to fish ingestion.

Autor:	Gonzalo Martínez de Velasco, Marta Rodero, Carmen Cuéllar, Tomás Chivato, José Mateos, Rafael Laguna
Předmět:	GASTROINTESTINAL diseases ALLERGIES PARASITE antigens KUDOA LABORATORY mice FISH as food ENZYME-linked immunosorbent assay PATIENTS
Zdroj:	Parasitology Research; Aug2008, Vol. 103 Issue 3, p713-715, 3p
Abstrakt:	Abstract  A majority of Kudoa spp. infects the somatic muscle of fish establishing cysts. Previously, elevated humoral responses were detected in BALB/c mice immunised with Kudoa sp. pseudocyst extracts and in BALB/c mice orally inoculated with Kudoa sp. pseudocysts, as well as the presence of anti-Kudoa sp. antibodies in human sera by enzyme-linked immunosorbent assay. The objective of this work was to test Kudoa sp. pseudocyst extracts by the skin prick test. Fifteen patients with gastroallergic and/or allergic symptoms related to fish ingestion were examined. Kudoa sp. pseudocyst extracts were administered (1 mg/ml) on the volar forearm skin. Four of the 15 selected patients were positive to Kudoa sp. extracts. The saline solution negative control did not induce any reaction. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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