| Autor: |
Norihisa Takahashi, Makiko Wakuta, Naoyuki Morishige, Tai-ichiro Chikama, Teruo Nishida, Yasuhiro Sumii |
| Předmět: |
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| Zdroj: |
Japanese Journal of Ophthalmology; May2007, Vol. 51 Issue 3, p185-190, 6p |
| Abstrakt: |
Abstract Purpose Diabetic complications are associated with abnormality of the basement membranes. We have developed a light-scattering detection system (LSDS) specifically for measurement of light scattering at the corneal epithelial basement membrane, and have determined the reproducibility and clinical significance of the results obtained by the LSDS in diabetic patients. Methods Thirty nondiabetic controls and 40 diabetic subjects participated in the study. Light scattering at the corneal epithelial basement membrane was measured with the LSDS. Results The measurement of light scattering at the corneal basement membrane was found to be reproducible. The LSDS index (mean SD) was 28.1 4.8 in controls, 35.7 6.3 in mild diabetic retinopathy subjects, and 42.7 8.6 in severe diabetic retinopathy subjects. This demonstrated that the LSDS index at the corneal basement membrane is proportional to the extent of diabetic retinopathy. Conclusions Measurement of light scattering at the corneal epithelial basement membrane is possible with the LSDS, is relatively easy to perform, and is reproducible. The LSDS may prove suitable for the early detection of diabetic ocular complications. Jpn J Ophthalmol 2007;51:185–190 Japanese Ophthalmological Society 2007 [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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