Synthesis of Phosphaisocoumarin Acids via Me3SiX-Mediated Dealkylation Reaction.

Autor: Ai-Yun Peng
Předmět:
Zdroj: Synthesis; Aug2008, Vol. 2008 Issue 15, p2412-2416, 5p
Abstrakt: The dealkylation of phosphaisocoumarin esters was studied under various conditions. An effective way to synthesize phosphaisocoumarin acids was developed via the reaction of phosphaisocoumarin esters with Me 3SiBr in chloroform followed by treatment with methanol, or with Me 3SiCl and NaI in acetonitrile followed by hydrolysis, under mild conditions in good to excellent yields. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index