Comparison of plasma levels of zinc and lead in esophageal cancer patients with normal subjects.

Autor: Salehifar, E., Khorasani, G., Shokrzade, M., Asadi, M., Shabankhani, B., Rezaeinejad, S.
Předmět:
Zdroj: Trace Elements & Electrolytes; 2008 3rd Quarter, Vol. 25 Issue 3, p165-168, 4p
Abstrakt: Objective: Esophageal cancer (EC) is a common disease in the north of Iran. Plumb (Pb) plasma level in EC patients has not been studied extensively and there are some controversial results regarding the value of zinc (Zn) in EC. The aim ofthis study was to compare the PB and Zn levels of patients with EC and healthy volunteers. Patients and methods: This study was conducted in Imam Hospital of Sari located in the north of Iran. 32 patients with EC diagnosis confirmed by pathological samples and 32 healthy volunteers who had a similar demographic characteristics with patients were included in the study. The plasma levels were determined by flame atomic absorption spectrophotometer. Results: EC patients had a lower Zn level compared to the matched healthy volunteers (1.28 ± 0.64 ppm vs. 2.13 ± 0.83 ppm, respectively; p-value < 0.001). The plasma Pb level was not different between the two groups (0.52 ± 0.15 ppm in EC patients and 0.56 ± 0.08 ppm in the control group). Conclusion: This study emphasizes the role of Zn deficiency as a risk factor for the development of EC. The consistency of our results with other studies would confirm the potential benefit of Zn supplementation for prevention of esophageal cancer in high risk individuals. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index