Functional Interaction Between ATP and TRPV1 Receptors.

Autor: Wang, Donna H., Tominaga, Makoto, Moriyama, Tomoko
Zdroj: Molecular Sensors for Cardiovascular Homeostasis; 2007, p133-140, 8p
Abstrakt: Noxious thermal, mechanical, or chemical stimuli evoke pain through excitation of the peripheral terminals called nociceptors.1,2 Many kinds of ionotropic and metabotropic receptors are involved in this process.3ȁ TRPV1, a capsaicin receptor, is a nociceptor-specific ion channel that serves as the molecular target of capsaicin, having six transmembrane domains with a short hydrophobic stretch between the fifth and sixth transmembrane domains.7 [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index