Ritonavir-Boosted Atazanavir, Methadone, and Ventricular Tachycardia: 2 Case Reports.

Autor: Gallagher, David P., Kieran, Jennifer, Sheehan, Gerard, Lambert, John, Mahon, Niall, G.^Mallon, Patrick W.
Předmět:
Zdroj: Clinical Infectious Diseases; 8/1/2008, Vol. 47 Issue 3, pe36-e38, 3p, 2 Diagrams
Abstrakt: We describe 2 cases of symptomatic ventricular tachycardia associated with prolonged QT interval. Both patients were infected with the human immunodeficiency virus and were receiving treatment with ritonavir-boosted atazanavir and methadone. Discontinuation of atazanavir in both cases resulted in a reduction in the QT interval and cessation of arrhythmia. We concluded that atazanavir contributed to prolonged corrected QT interval and subsequent ventricular tachycardia. [ABSTRACT FROM AUTHOR]
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