Non-Gl-Malignancy-Related Malabsorption Leads to Malnutrition and Weight Loss.

Autor: Mantovani, Giovanni, Anker, Stefan D., Morley, John E., Fanelli, Filippo Rossi, Scevola, Daniele, Schuster, Michael W., Shing-Shing Yeh, Suzuki, Susumu, Goncalves, Carolina G., Ramos, Eduardo J. B., Asakawa, Akihiro, Inui, Akio, Meguid, Michael M.
Zdroj: Cachexia & Wasting: A Modern Approach; 2006, p509-519, 11p
Abstrakt: Approximately 80% of patients with advanced-stage cancer have cancer anorexia-cachexia syndrome (CACS), in which one of the main manifestations is malnutrition [1]. CACS is characterised by anorexia, decreased food intake, tissue wasting, and body weight loss. It is also associated with changes in lipid, protein, and carbohydrate metabolism, leading to a decrease in fat and muscle mass, which independently influence mortality in cancer patients [2] [5]. Anorexia and reduced food intake occur during growth of the tumour, thus compromising host defences which, in turn, detrimentally influences outcome [1]. Reduced food intake and malabsorption reduce energy intake, even though energy expenditure is increased [6] [8]. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index