| Autor: |
E. Righi, C. Giacomazzi, V. Lindstrom, A. Albarello, O. Soro, M. Miglino, M. Perotti, O. Varnier, M. Gobbi, C. Viscoli, M. Bassetti |
| Zdroj: |
Mycopathologia; Jun2008, Vol. 165 Issue 6, p407-410, 4p |
| Abstrakt: |
Abstract Cunninghamella bertholletiae infection occurs most frequently in neutropenic patients affected by haematological malignancies, is associated with an unfavourable outcome. We report a case of rhino-mastoidal fungal infection in a leukaemic patient. Bioptical tissue cultures yield the isolation of a mould with typical properties of Cunninghamella species. Liposomal amphotericin B (L-Amb) therapy combined with surgical intervention brought the lesion to recovery. Nevertheless, the patient died 14 days after bone marrow transplantation (BMT) from bacterial sepsis. Mastoiditis was documented at CT-scan. The conditioning regimen probably caused the reactivation of the Cunninghamella infection that led to the patient’s fatal outcome; fungal hyphae were detected after autopsy of brain and lung tissue. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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