Autor: |
Ahmet Isik, Bilal Ustundag, Kerem Metin, Kader Aksoy |
Předmět: |
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Zdroj: |
Inflammation; Jun2008, Vol. 31 Issue 3, p146-153, 8p, 4 Charts |
Abstrakt: |
Abstract Hepcidin is a principal iron regulatory hormone and its expression is stimulated by cytokines. The aim of this study was to determine serum levels of the prohormone form of hepcidin, pro-hepcidin, in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The study included 72 RA and 28 SLE patients and 33 healthy controls (HC). Serum iron status, tumor necrosis factor (TNF)-α, interleukin (IL)-6 and pro-hepcidin levels were determined. Pro-hepcidin levels in the RA group was higher than SLE and HC groups (p p r = 0.459, p r = 0.374, p r = −0.603, p [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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