The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats.
Autor: | Schäfer, A., Pfrang, J., Neumüller, J., Fiedler, S., Ertl, G., Bauersachs, J., Schäfer, A, Neumüller, J |
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Předmět: |
CANNABINOIDS
LABORATORY rats BLOOD platelet activation CHEMOKINES TYPE 2 diabetes LEUCOCYTES METABOLIC syndrome MONOCYTES ANIMAL experimentation ANTI-inflammatory agents BIOLOGICAL models BLOOD platelet aggregation CELL receptors COMPARATIVE studies CYTOKINES ENZYME-linked immunosorbent assay FLOW cytometry HETEROCYCLIC compounds INFLAMMATORY mediators LIPIDS RESEARCH methodology MEDICAL cooperation PIPERIDINE RATS RESEARCH TIME WEIGHT gain EVALUATION research GLUCOSE intolerance PLATELET aggregation inhibitors LEUKOCYTE count PLATELET count PHARMACODYNAMICS |
Zdroj: | British Journal of Pharmacology; Jul2008, Vol. 154 Issue 5, p1047-1054, 8p, 1 Chart, 3 Graphs |
Abstrakt: | |
Databáze: | Complementary Index |
Externí odkaz: |