| Autor: |
Rzheznikov, V., Golubovskaya, L., Minailova, O., Keda, B., Ivanenko, T., Fedotov, V., Sushinina, L., Titova, T., Tolkachev, V., Osetrova, I., Smirnova, Z. |
| Předmět: |
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| Zdroj: |
Pharmaceutical Chemistry Journal; Oct2007, Vol. 41 Issue 10, p523-526, 4p, 1 Diagram, 2 Charts |
| Abstrakt: |
Antitumor steroids with a cytotoxic substituent attached to the steroid nucleus without participation of natural functional groups have been obtained by esterification of 3-acetates of 11α-hydroxy derivatives of estradiol and 17α-ethinylestradiol with para-[bis(2-chloroethyl)amino]phenylacetic acid using the carbodiimide method. Some substances of this series combine antitumor activity and antiestrogen properties. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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